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簡(jiǎn)要描述:HECT E3 ubiquitin ligase is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
產(chǎn)品型號(hào):bs-15445R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-02-26
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